Tg(Tyrp1-cre)1Ipc - Mesenchyme Recombinase Activity Detail MGI Mouse

Tg(Tyrp1-cre)1Ipc - Mesenchyme
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(Tyrp1-cre)1Ipc
transgene insertion 1, I Pierre Chambon

Driver: Tyrp1
Type: Transgenic (Recombinase)

Synonym:

Cre^Trp1, TRP1-Cre

Molecular description:

The transgenic construct contained the Tyrp1 promoter region adjoined to 2 rabbit Beta-globin exons and the cre coding region followed by a polyA signal. The Tyrp1 promoter primarily drives expression in the retinal pigment epithelium. Expression was also detected in the ciliary margin of the retina and in the neural retina. Expression was not detected in the embryonic periocular mesenchyme or the choroid.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(Tyrp1-cre)1Ipc activity also observed in:
alimentary system, embryo-other, head, nervous system, sensory organs

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

20 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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