|
|
|
Allele Information
|
|
Allele:
|
Tg(Ins2-cre)25Mgn
transgene insertion 25, Mark A Magnuson
|
Driver: Ins2
Type: Transgenic (Cre/Flp)
|
|
|
Synonym:
|
Ins2cre, RIPCre, RIP2-cre, [RIP]-Cre, Rip-cre, RIP Cre, Ins-Cre
|
|
Molecular description:
|
This transgene expresses Cre recombinase under the control of the rat insulin promoter (Ins2), which is active in pancreatic beta cells and in neurons of the hypothalamus. 9 copies of the transgene are estimated to be present.
|
|
Find mice (IMSR):
|
Mouse Strains:
1 lines available
Cell Lines:
0 lines available
|
|
Additional Tissues:
|
Tg(Ins2-cre)25Mgn activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
integumental system,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
sensory organs,
skeletal system,
tail
(less)
|
|
|
Tissue Information
|
|
Endocrine System
|
Other recombinase alleles with activity in Endocrine System tissues:
1700009P17Riktm1.1(icre)Heli,
Ccktm1.1(cre)Zjh,
Cpa1tm1(cre/ERT2)Dam,
Fgf16tm1.1(cre)Sms,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Krt19tm1(cre/ERT)Ggu,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Ptf1atm1.1(cre)Cvw,
Shhtm1(EGFP/cre)Cjt,
Ssttm2.1(cre)Zjh,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Camk2a-cre)1Nobs,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cga-cre)3Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-cre)ACmk,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Ela1-cre)16Eps,
Tg(Ela1-cre/ERT2)1Stof,
Tg(Fabp4-cre)1Rev,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(GFAP-cre)25Mes,
Tg(Gh1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins2-cre)23Herr,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(Lhb-cre)1Sac,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre)89.1Dam,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pf4-cre)Q3Rsko,
Tg(Pgk1-cre)1Lni,
Tg(Pitx1-cre)1Rsd,
Tg(Pomc-cre)5Brn,
Tg(Prm-cre)58Og,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(REN-cre)1Haca,
Tg(Sim1-cre)1Lowl,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Th-cre)12Mrub,
Tg(Th-cre)1Tmd,
Tg(Thy1-cre)1Vln,
Tg(TPO-cre)1Shk,
Tg(Tyr-cre)1Gfk,
Tg(Vav1-cre)8Cgp,
Tg(Vil-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Thtm1(cre)Te,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
|
|
|
Images
|
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail.
Reset Images
J:193672
Fig. EIIa Pancreas Adult
J:193672
Fig. Ins2 Pancreas P7
J:51826
Fig. 4
J:69314
Fig. 1
|
|
Recombinase Activity
|
Click heading to resort table.
|
|
References
|
|
Analysis Tools