The "laboratory mouse" originated from a mixture of M. m. domesticus, M. m. musculus, and M. m. molossius subspecies. An inbred strain of the laboratory mouse is defined as a strain that has been brother/sister mated for 20 or more consecutive generations and can be traced to a single ancestral pair. For further information about inbred strains of mice see Strains, SNPs and Polymorphisms.
On the Mouse Facts pages, you will find information on these topics:
| 2,716,965,481 bp | Reference assembly (C57BL/6J, "golden path") length: the sum of non-redundant top level sequence regions (J:80507). |
| 2.5 x 109 bp | Mouse Genome Sequencing Consortium. 2002. Initial sequencing and comparative analysis of the mouse genome. Nature 420: 520-562. |
| 1355.5 cM | BSS and BSB crosses: Rowe LB; Barter ME; Kelmenson JA; Eppig J. 2003. Genome Res 13(1):122-33 (J:81431). |
| 1450 cM | Copeland, NG, et al. 1993. Science 62:57-66. (J:14384). |
| 1360.9 cM | Dietrich, WF et al. 1996. Nature Mar 14:380(6570)149-52 ( J:34212). |
Mapped Length represents the (MGI) estimated cM position of the most distally placed locus on that chromosome.
Total Estimated Size omits centromeres and telomeres which would add, on average, ~8 Mb per chromosome or ~160 Mb to the genome. It also omits uncaptured gaps between supercontigs.
| Chromosome | Mapped Length (cM) | Total Estimated Size (M bp) (NCBI build 37) |
|---|---|---|
| 1 | 112.0 | 197 |
| 2 | 114.0 | 182 |
| 3 | 95.0 | 160 |
| 4 | 84.0 | 156 |
| 5 | 92.0 | 153 |
| 6 | 75.0 | 150 |
| 7 | 74.0 | 153 |
| 8 | 82.0 | 132 |
| 9 | 79.0 | 124 |
| 10 | 82.0 | 130 |
| 11 | 104.0 | 122 |
| 12 | 66.0 | 121 |
| 13 | 80.0 | 120 |
| 14 | 69.0 | 125 |
| 15 | 74.6 | 103 |
| 16 | 72.0 | 98 |
| 17 | 58.0 | 95 |
| 18 | 59.0 | 91 |
| 19 | 57.0 | 15.9 |
| X | 167 | |
| Y | 0.016 | |
| MT | 0.016 | |
| Total: | 1528.6 | 2594.932 |
The estimates below are based on information in Biology of the Laboratory Mouse (the Staff of The Jackson Laboratory, E. Green, ed. 1966, Dover Publications, New York) and in the Mouse Phenome Database (MPD) at the Jackson Laboratory.
Note: Strain variation can affect these values significantly.
General
Body weight: average ~20 g; highly variable
Animal Resources Body Weight Study of 1993 (growth charts for selected strains)
Mouse Phenome Database: body weight
Body Temperature: ~36.9 C (in addition to strain, variables are age, sex, environmental conditions)
Lifespan: 1.3 - 3 years; highly variable
Reproduction
Sexual maturity: after ~4 weeks of age; highly variableCirculation
Estrus cycle frequency: every ~4-5 days
Gestation: Average 19-21 days
Litter size: usually 1-10 pups - highly variable due to genetic and environmental factors; tends to increase for the first few litters, then decrease with age
Reproductive lifespan of a female: approaches 2 years in some strains
Lactation: duration ~4 weeks
Mouse Phenome Database: reproductive performance
Total serum protein: ~4-7 g/100 mlRespiration
Blood volume: ~5.5 ml per 100 g body weight
Heart rate: Adult: 632 +/- 51.3 beats per minute; Newborn: 286 +/- 56.8 beats per minute
Mouse Phenome Database: cardiovascular
Systolic pressure: 83-164 mm Hg
Blood pH: 7.3-7.4
Mouse Phenome Database: pH, blood chemistry
Respiratory rate: ~163 per minute
Mouse Phenome Database: respiratory function
Tidal volume: ~0.15 ml
Urinary Tract
Average urine output: ~1.6 ml per 24 hr
Average water intake: ~ 5 ml per 24 hr
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2008 MGI_4.01 Web browser compatibility |
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