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Mammalian Phenotype Ontology Annotations
Query Results - Summary
bromodomain containing 2
131 phenotypes from 6 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
decreased CD8-positive, alpha-beta T cell number J:211773
decreased KLRG1+ CD8 alpha beta T cell number J:211773
decreased mature B cell number J:211773
increased CD4-positive, alpha beta T cell number J:211773
increased mean corpuscular hemoglobin J:211773
increased or absent threshold for auditory brainstem response J:211773
abnormal adenohypophysis morphology J:239583
abnormal aortic valve morphology J:239583
abnormal brain artery topology J:239583
abnormal choroid plexus morphology J:239583
abnormal common carotid artery morphology J:239583
abnormal ductus venosus morphology J:239583
abnormal ductus venosus topology J:239583
abnormal external carotid artery origin J:239583
abnormal forebrain morphology J:239583
abnormal gallbladder morphology J:239583
abnormal hepatic portal vein connection J:239583
abnormal hypoglossal nerve topology J:239583
abnormal interatrial septum morphology J:239583
abnormal lung position or orientation J:239583
abnormal middle ear ossicle morphology J:239583
abnormal Mullerian duct topology J:239583
abnormal nasal septum morphology J:239583
abnormal olfactory nerve morphology J:239583
abnormal optic chiasm morphology J:239583
abnormal optic cup morphology J:239583
abnormal optic stalk morphology J:239583
abnormal pectinate muscle morphology J:239583
abnormal physiological umbilical hernia morphology J:239583
abnormal pineal gland morphology J:239583
abnormal pulmonary valve morphology J:239583
abnormal semilunar valve morphology J:239583
abnormal thymus topology J:239583
abnormal umbilical vein topology J:239583
abnormal vagus ganglion morphology J:239583
abnormal vertebral arch morphology J:239583
abnormal vertebral artery topology J:239583
abnormal vertebral body morphology J:239583
absent connection between subcutaneous lymph vessels and lymph sac J:239583
absent costovertebral joint J:239583
absent eye muscles J:239583
absent pectinate muscle J:239583
absent superior cervical ganglion J:239583
absent vagus nerve J:239583
absent vertebral arch J:239583
aorta coarctation J:239583
aphakia J:239583
artery stenosis J:239583
atrioventricular septal defect J:239583
basisphenoid bone foramen J:239583
blood in lymph vessels J:239583
common truncal valve J:239583
decreased rib number J:239583
double outlet right ventricle J:239583
dual inferior vena cava J:239583
duplication of ductus venosus J:239583
enlarged brain ventricles J:239583
enlarged heart J:239583
enlarged liver sinusoidal spaces J:239583
exencephaly J:239583
fetal growth retardation J:239583
fusion of vertebral arches J:239583
hemorrhage J:239583
heterochrony J:239583
increased rib number J:239583
interrupted aortic arch, type b J:239583
muscular ventricular septal defect J:239583
myelocele J:239583
perimembraneous ventricular septal defect J:239583
persistent right dorsal aorta J:239583
persistent trigeminal artery J:239583
persistent truncus arteriosis J:239583
preweaning lethality, complete penetrance J:211773
reduced sympathetic cervical ganglion size J:239583
retroesophageal right subclavian artery J:239583
retropleural edema J:239583
rib bifurcation J:239583
rib fusion J:239583
scoliosis J:239583
small kidney J:239583
small thymus J:239583
small thyroid gland J:239583
subcutaneous edema J:239583
thin myocardium compact layer J:239583
thoracoschisis J:239583
transposition of great arteries J:239583
involves: 129P2/OlaHsd * C57BL/6J
abnormal embryo size J:147040
decreased cell proliferation J:147040
involves: 129P2/OlaHsd * C57BL/6J
abnormal cell cycle J:147040
abnormal cell death J:147040
abnormal neural tube closure J:147040
decreased cell proliferation J:147040
decreased embryo size J:147040
embryonic lethality during organogenesis, complete penetrance J:147040
increased embryonic tissue cell apoptosis J:147040
abnormal adipose tissue morphology J:159964
abnormal blood homeostasis J:159964
abnormal circulating lipid level J:159964
abnormal eating behavior J:159964
abnormal pancreatic islet morphology J:159964
abnormal respiratory quotient J:159964
decreased circulating glucose level J:159964
hepatic steatosis J:159964
improved glucose tolerance J:159964
increased basal metabolism J:159964
increased circulating adiponectin level J:159964
increased circulating cholesterol level J:159964
increased circulating glucagon level J:159964
increased circulating insulin level J:159964
increased circulating interleukin-1 beta level J:159964
increased circulating leptin level J:159964
increased circulating triglyceride level J:159964
increased circulating tumor necrosis factor level J:159964
increased epididymal fat pad weight J:159964
increased fat cell size J:159964
increased interscapular fat pad weight J:159964
increased pancreatic beta cell number J:159964
increased pancreatic islet number J:159964
increased total body fat amount J:159964
obese J:159964
pancreatic islet hyperplasia J:159964
perinatal lethality, incomplete penetrance J:159964
postnatal lethality, incomplete penetrance J:159964
involves: CD-1
abnormal cell cycle J:188139
abnormal craniofacial morphology J:188139
abnormal embryonic neuroepithelial layer differentiation J:188139
abnormal embryonic neuroepithelium morphology J:188139
abnormal neural tube morphology J:188139
embryonic growth retardation J:188139
embryonic lethality during organogenesis, complete penetrance J:188139
increased embryonic neuroepithelium apoptosis J:188139
increased embryonic neuroepithelium thickness J:188139
involves: CD-1
normal embryo phenotype J:188139
involves: CD-1
no abnormal phenotype detected J:188139

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory