Arf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arf4
ADP-ribosylation factor 4
MGI:99433

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arf4^{Gt(AY0614)Wtsi}/Arf4^{Gt(AY0614)Wtsi} involves: 129P2/OlaHsd * C57BL/6	abnormal visceral endoderm morphology	J:215153
	decreased embryo size	J:215153
	normal embryo phenotype	J:215153
	embryonic lethality during organogenesis, complete penetrance	J:215153
	incomplete embryo turning	J:215153
Arf4^{Gt(CSH658)Byg}/Arf4⁺ B6.129P2-Arf4^{Gt(CSH658)Byg}	abnormal response to novelty	J:192108
	normal behavior/neurological phenotype	J:192108
	decreased dendritic spine density	J:192108
	decreased miniature excitatory postsynaptic current amplitude	J:192108
Arf4^{Gt(CSH658)Byg}/Arf4^{Gt(CSH658)Byg} B6.129P2-Arf4^{Gt(CSH658)Byg}	embryonic lethality, complete penetrance	J:192108
Arf4^tm1.1Tsdk/Arf4^tm1.1Tsdk B6J.B6N-Arf4^tm1.1Tsdk	embryonic lethality, complete penetrance	J:279779
Arf4^{tm1b(KOMP)Wtsi}/Arf4⁺ C57BL/6N-Arf4^{tm1b(KOMP)Wtsi}/Ucd	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	increased spleen weight	J:211773
Arf4^{tm1b(KOMP)Wtsi}/Arf4^{tm1b(KOMP)Wtsi} C57BL/6N-Arf4^{tm1b(KOMP)Wtsi}/Ucd	abnormal embryo size	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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