Scn1b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scn1b
sodium channel, voltage-gated, type I, beta
MGI:98247

18 phenotypes from 5 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scn1b^em1(IMPC)H/Scn1b^em1(IMPC)H C57BL/6NTac-Scn1b^em1(IMPC)H/H	preweaning lethality, incomplete penetrance	J:211773
Scn1b^tm1.1Bion/Scn1b⁺ Not Specified	abnormal action potential	J:163771
	abnormal nervous system electrophysiology	J:163771
	environmentally induced seizures	J:163771
Scn1b^tm1.1Bion/Scn1b^tm1.1Bion Not Specified	abnormal brain wave pattern	J:163771
	environmentally induced seizures	J:163771
	postnatal growth retardation	J:163771
	premature death	J:163771
	seizures	J:163771
	tonic-clonic seizures	J:163771
	tremors	J:163771
Scn1b^tm1Isom/Scn1b^tm1Isom involves: 129X1/SvJ * C57BL/6	abnormal action potential	J:90136
	abnormal axon morphology	J:90136
	abnormal nervous system morphology	J:90136
	abnormal optic nerve morphology	J:90136
	ataxia	J:90136
	lethality at weaning, complete penetrance	J:90136
	normal nervous system phenotype	J:90136
	postnatal growth retardation	J:90136
	seizures	J:90136
Scn1b^tm2.1Isom/Scn1b^tm2.1Isom involves: 129X1/SvJ * C57BL/6	ataxia	J:128713
	postnatal growth retardation	J:128713
	postnatal lethality, complete penetrance	J:128713
	seizures	J:128713
Scn1b^tm2Isom/Scn1b^tm2Isom involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:128713

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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