Pth Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pth
parathyroid hormone
MGI:97799

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pth^{tm1a(EUCOMM)Wtsi}/Pth^{tm1a(EUCOMM)Wtsi} C57BL/6N-Pth^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal retina morphology	J:211773
	decreased circulating calcium level	J:211773
	increased bone mineral density	J:211773
Pth^tm1Dgo/Pth^tm1Dgo involves: 129S2/SvPas * C57BL/6J	abnormal angiogenesis	J:76407
	abnormal bone mineralization	J:76407
	abnormal bone structure	J:76407
	abnormal cartilage development	J:76407
	abnormal cranium morphology	J:76407
	abnormal osteoclast morphology	J:76407
	abnormal skeleton development	J:76407
	abnormal trabecular bone morphology	J:76407
	decreased length of long bones	J:76407
	decreased osteoblast cell number	J:76407
	decreased osteoclast cell number	J:76407
	enlarged parathyroid gland	J:76407
	increased compact bone thickness	J:76407
	increased osteoblast apoptosis	J:76407
	increased osteocyte apoptosis	J:76407
	increased width of hypertrophic chondrocyte zone	J:76407
	short metacarpal bones	J:76407
	short metatarsal bones	J:76407
	small vertebral body	J:76407

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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