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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Prkch
protein kinase C, eta
MGI:97600
33 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Prkchtm1.2Gasc/Prkchtm1.2Gasc
involves: C57BL/6 * FVB/N * SJL
abnormal brachial lymph node morphology J:186080
abnormal cervical lymph node morphology J:186080
abnormal effector T cell morphology J:186080
abnormal lymph node morphology J:186080
decreased B cell number J:186080
decreased CD4-positive, alpha-beta T cell number J:186080
decreased CD8-positive, alpha-beta T cell number J:186080
decreased DN1 thymic pro-T cell number J:186080
decreased DN4 thymocyte number J:186080
decreased double-positive T cell number J:186080
decreased lymphocyte cell number J:186080
decreased T cell number J:186080
decreased T cell proliferation J:186080
enlarged axillary lymph nodes J:186080
enlarged cervical lymph nodes J:186080
enlarged inguinal lymph nodes J:186080
enlarged lymph nodes J:186080
increased B cell number J:186080
increased CD4-positive, alpha-beta T cell number J:186080
increased CD8-positive, alpha-beta T cell number J:186080
increased memory T cell number J:186080
increased T cell number J:186080
thymus hypoplasia J:186080
Prkchtm1b(EUCOMM)Hmgu/Prkchtm1b(EUCOMM)Hmgu
B6N(Cg)-Prkchtm1b(EUCOMM)Hmgu/J
decreased grip strength J:211773
increased lean body mass J:211773
Prkchtm1Cda/Prkchtm1Cda
B6.129S-Prkchtm1Cda
delayed wound healing J:83498
impaired wound healing J:83498
Prkchtm1Cda/Prkchtm1Cda
involves: 129S/SvEv * C57BL/6J
abnormal eyelid aperture J:83498
decreased body weight J:83498
epidermal hyperplasia J:83498
increased incidence of tumors by chemical induction J:83498
increased skin papilloma incidence J:83498
postnatal lethality, incomplete penetrance J:83498

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory