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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pou1f1
POU domain, class 1, transcription factor 1
MGI:97588
40 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pou1f1dw-J/Pou1f1dw-J
C3H/HeJ-Pou1f1dw-J/J
abnormal cerebellar foliation J:110624
abnormal cerebellar granule layer morphology J:110624
abnormal cerebellum development J:110624
abnormal dentate gyrus morphology J:110624
abnormal hippocampus pyramidal cell layer J:110624
abnormal hippocampus pyramidal cell morphology J:110624
decreased hippocampus pyramidal cell number J:110624
ectopic cerebellar granule cells J:110624
Pou1f1dw/Pou1f1dw-J
(DW/J x C3H/HeJ)F1
extended life span J:73731
Pou1f1dw/Pou1f1dw
DW/J Pou1f1dw
abnormal adenohypophysis morphology J:108961
absent lactotrophs J:7211
absent somatotrophs J:7211
adenohypophysis hypoplasia J:108961
decreased B cell number J:110683
decreased body size J:108961
extended life span J:73731
increased pituitary gland apoptosis J:108961
Pou1f1dw/Pou1f1dw
Not Specified
abnormal actin cytoskeleton morphology J:144823
abnormal cochlear outer hair cell morphology J:144823
abnormal hair cell physiology J:144823
abnormal Hensen stripe morphology J:144823
abnormal molar root morphology J:13120
abnormal orientation of outer hair cell stereociliary bundles J:144823
abnormal pillar cell morphology J:144823
abnormal stria vascularis morphology J:144823
abnormal strial intermediate cell morphology J:144823
abnormal tectorial membrane morphology J:144823
abnormal tectorial membrane striated-sheet matrix morphology J:144823
abnormal tunnel of Corti morphology J:144823
absent cochlear microphonics J:144823
absent distortion product otoacoustic emissions J:144823
absent lactotrophs J:6754
absent somatotrophs J:7211
cochlear outer hair cell degeneration J:144823
deafness J:144823
decreased circulating prolactin level J:6754
decreased endocochlear potential J:144823
decreased growth hormone level J:6589
decreased prolactin level J:6589
decreased thyrotroph cell number J:12161
infertility J:13120
proportional dwarf J:13120
short cochlear outer hair cells J:144823

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory