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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
MGI:97385
43 phenotypes from 7 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ntrk3tm1.1Tes/Ntrk3tm1.1Tes
involves: 129S1/Sv
retinal ganglion cell degeneration J:171397
normal vision/eye phenotype J:171397
Ntrk3tm1Bbd/Ntrk3tm1Bbd
involves: 129S2/SvPas * C57BL/6
abnormal cochlear IHC afferent innervation pattern J:29245
abnormal cochlear sensory epithelium morphology J:29245
abnormal lumbar dorsal root ganglion morphology J:17195
abnormal sensory neuron innervation pattern J:17195
athetotic walking movements J:17195
normal behavior/neurological phenotype J:17195
decreased body size J:17195
impaired coordination J:17195
impaired limb coordination J:17195
limb grasping J:17195
postnatal lethality J:17195
premature death J:17195
small cochlear ganglion J:29245
small vestibular ganglion J:29245
Ntrk3tm1Ddg/Ntrk3tm1Ddg
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:99603
Ntrk3tm1Kln/Ntrk3tm1Kln
involves: 129P2/OlaHsd * C57BL/6
abnormal cochlear nerve morphology J:75365
decreased sensory neuron number J:75365
Ntrk3tm1Par/Ntrk3tm1Par
involves: 129S1/Sv
decreased sensory neuron number J:44286
postnatal lethality, complete penetrance J:44286
Ntrk3tm1Par/Ntrk3tm1Par
involves: 129S1/Sv * C57BL/6
abnormal aortic valve morphology J:45083
abnormal cardiac outflow tract development J:45083
abnormal cranial ganglia morphology J:45083
abnormal heart septum morphology J:45083
abnormal heart shape J:45083
abnormal heart valve morphology J:45083
abnormal mitral valve morphology J:45083
abnormal proprioceptive neuron morphology J:45083
abnormal pulmonary vein morphology J:45083
abnormal tricuspid valve morphology J:45083
abnormal truncus arteriosus septation J:45083
decreased sensory neuron number J:45083
dilated heart right ventricle J:45083
enlarged heart J:45083
enlarged pulmonary valve J:45083
lung hemorrhage J:45083
ostium secundum atrial septal defect J:45083
postnatal lethality, complete penetrance J:45083
pulmonary valve stenosis J:45083
small cochlear ganglion J:45083
small L5 dorsal root ganglion J:45083
small nodose ganglion J:45083
small petrosal ganglion J:45083
small trigeminal ganglion J:45083
small vestibular ganglion J:45083
ventricular septal defect J:45083
Ntrk3tm2.1Ddg/Ntrk3tm2.1Ddg
involves: 129S6/SvEvTac * C57BL/6
neonatal lethality, complete penetrance J:227979
Ntrk3tm3.1(cre/ERT2)Ddg/Ntrk3tm3.1(cre/ERT2)Ddg
involves: 129S6/SvEvTac * C57BL/6
neonatal lethality, complete penetrance J:227979

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory