Ngf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ngf
nerve growth factor
MGI:97321

40 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ngf^tm1.1Blhe/Ngf⁺ B6.Cg-Ngf^tm1.1Blhe	abnormal heart left ventricle morphology	J:190893
	abnormal myocardial fiber morphology	J:190893
	abnormal myocardium layer morphology	J:190893
	abnormal vascular endothelial cell morphology	J:190893
	abnormal vascular endothelial cell physiology	J:190893
	decreased cardiac muscle contractility	J:190893
	dilated cardiomyopathy	J:190893
	dilated heart left ventricle	J:190893
	dilated heart right ventricle	J:190893
	edema	J:190893
	increased vascular permeability	J:190893
	premature death	J:190893
	thin myocardium	J:190893
Ngf^tm1.1Blhe/Ngf⁺ Tg(Cspg4-DsRed.T1)1Akik/0 B6.Cg-Ngf^tm1.1Blhe Tg(Cspg4-DsRed.T1)1Akik	abnormal pericyte morphology	J:190893
Ngf^tm1Gne/Ngf⁺ involves: 129S7/SvEvBrd	abnormal cholinergic neuron morphology	J:282017
	abnormal object recognition memory	J:282017
	impaired spatial learning	J:282017
Ngf^tm1Gne/Ngf⁺ involves: 129S7/SvEvBrd * C57BL/6	abnormal pain threshold	J:17792
Ngf^tm1Gne/Ngf⁺ involves: 129S7/SvEvBrd * C57BL/6	dorsal root ganglion hypoplasia	J:17792
Ngf^tm1Gne/Ngf^tm1Gne involves: 129S7/SvEvBrd	abnormal dorsal root ganglion morphology	J:154926
Ngf^tm1Gne/Ngf^tm1Gne involves: 129S7/SvEvBrd	normal nervous system phenotype	J:154926
Ngf^tm1Gne/Ngf^tm1Gne involves: 129S7/SvEvBrd * C57BL/6	abnormal gait	J:17792
	abnormal hair growth	J:17792
	abnormal sensory neuron innervation pattern	J:17792
	abnormal sympathetic ganglion morphology	J:17792
	absent superior cervical ganglion	J:17792
	blepharoptosis	J:17792
	decreased body size	J:17792
	decreased body weight	J:17792
	delayed eyelid opening	J:17792
	dorsal root ganglion hypoplasia	J:17792
	hypoalgesia	J:17792
	postnatal growth retardation	J:17792
	postnatal lethality, incomplete penetrance	J:17792
	small superior cervical ganglion	J:17792
	tremors	J:17792
Ngf^tm2.1Blhe/Ngf⁺ B6.Cg-Ngf^tm2.1Blhe	no abnormal phenotype detected	J:190893
Tg(Ngf)47Kma/0 involves: C57BL/6 * CBA/J	abnormal innervation	J:17131
	abnormal sensory neuron innervation pattern	J:17131
	superior cervical ganglion hypertrophy	J:17131
	trigeminal ganglion hypertrophy	J:17131
Tg(Ngf)56Kma/0 involves: C57BL/6 * CBA/J	abnormal innervation	J:17131
	abnormal sensory neuron innervation pattern	J:17131
	decreased body size	J:17131
	slow postnatal weight gain	J:17131
	superior cervical ganglion hypertrophy	J:17131
	trigeminal ganglion hypertrophy	J:17131

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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