84 phenotypes from 8 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nedd4Gt(OST16211)Lex/Nedd4+ involves: 129S5/SvEvBrd * C57BL/6J	decreased body weight	J:103485
Nedd4Gt(OST16211)Lex/Nedd4Gt(OST16211)Lex involves: 129S5/SvEvBrd * C57BL/6J	neonatal lethality	J:103485
Nedd4Gt(XA209)Byg/Nedd4+ involves: 129P2/OlaHsd	decreased birth weight	J:207675
	decreased fetal weight	J:207675
	postnatal growth retardation	J:207675
Nedd4Gt(XA209)Byg/Nedd4Gt(XA209)Byg B6.129P2-Nedd4Gt(XA209)Byg	abnormal meiosis	J:320185
	abnormal Sertoli cell development	J:320185
	abnormal sex determination	J:320185
	abnormal testis development	J:320185
	fetal growth retardation	J:320185
	lethality throughout fetal growth and development, complete penetrance	J:320185
	primary sex reversal	J:320185
	sex reversal	J:320185
	small gonad	J:320185
Nedd4Gt(XA209)Byg/Nedd4Gt(XA209)Byg involves: 129P2/OlaHsd	abnormal cranial ganglia morphology	J:203994
	abnormal craniofacial bone morphology	J:203994
	abnormal craniofacial morphology	J:203994
	abnormal frontal bone morphology	J:203994
	abnormal glossopharyngeal ganglion morphology	J:203994
	abnormal mandible morphology	J:203994
	abnormal maxilla morphology	J:203994
	abnormal neural crest cell physiology	J:203994
	abnormal premaxilla morphology	J:203994
	abnormal T cell activation	J:143560
	abnormal temporal bone tympanic part morphology	J:203994
	abnormal tongue position	J:203994
	abnormal vagus ganglion morphology	J:203994
	absent palate bones	J:203994
	centrally nucleated skeletal muscle fibers	J:207675
	cleft palate	J:203994
	decreased B cell number	J:143560
	decreased birth weight	J:207675
	decreased bone mass	J:203994
	decreased bone mineral density	J:203994
	decreased bone ossification	J:203994
	decreased cranial neural crest cell number	J:203994
	decreased embryo size	J:203994, J:207675
	decreased fetal size	J:207675
	decreased fetal weight	J:207675
	decreased fibroblast proliferation	J:207675
	decreased IgG1 level	J:143560
	decreased IgG2b level	J:143560
	decreased IgG3 level	J:143560
	decreased interleukin-2 secretion	J:143560
	decreased T cell proliferation	J:143560
	delayed muscle development	J:207675
	increased CD4-positive, alpha-beta T cell number	J:143560
	increased CD8-positive, alpha-beta T cell number	J:143560
	increased cranial neural crest cell apoptosis	J:203994
	increased embryonic neuroepithelium apoptosis	J:203994
	increased IgM level	J:143560
	increased T cell number	J:143560
	increased variability of skeletal muscle fiber size	J:207675
	palatal shelves fail to meet at midline	J:203994
	perinatal lethality, complete penetrance	J:143560, J:207675
	preweaning lethality, complete penetrance	J:207675
	prominent forehead	J:203994
	small basioccipital bone	J:203994
	small exoccipital bone	J:203994
	small mandible	J:203994
	small maxilla	J:203994
	small trigeminal ganglion	J:203994
	small vertebrae	J:203994
	underdeveloped hair follicles	J:207675
Nedd4Gt(XB398)Byg/Nedd4Gt(XB398)Byg involves: 129P2/OlaHsd	decreased B cell number	J:143560
	decreased IgG1 level	J:143560
	decreased IgG2b level	J:143560
	decreased IgG3 level	J:143560
	decreased interleukin-2 secretion	J:143560
	decreased T cell proliferation	J:143560
	increased CD4-positive, alpha-beta T cell number	J:143560
	increased CD8-positive, alpha-beta T cell number	J:143560
	increased IgM level	J:143560
	increased T cell number	J:143560
	perinatal lethality, complete penetrance	J:143560
	preweaning lethality, complete penetrance	J:207675
Nedd4Gt(XB786)Byg/Nedd4Gt(XB786)Byg involves: 129P2/OlaHsd	prenatal lethality, complete penetrance	J:137202
Nedd4tm1Bros/Nedd4tm1Bros Not Specified	prenatal lethality, complete penetrance	J:137202
Nedd4tm2b(EUCOMM)Hmgu/Nedd4+ C57BL/6N-Nedd4tm2b(EUCOMM)Hmgu/H	abnormal behavior	J:211773
	abnormal gait	J:211773
	decreased circulating creatinine level	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
	impaired glucose tolerance	J:211773
	increased grip strength	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
	tremors	J:211773
Nedd4tm2b(EUCOMM)Hmgu/Nedd4tm2b(EUCOMM)Hmgu C57BL/6N-Nedd4tm2b(EUCOMM)Hmgu/H	preweaning lethality, complete penetrance	J:211773
Nedd4tm2Bros/Nedd4tm2Bros involves: C57BL/6N	abnormal dendrite morphology	J:164745
	abnormal miniature excitatory postsynaptic currents	J:164745
	abnormal neuron morphology	J:164745
	abnormal synapse morphology	J:164745
	abnormal synaptic vesicle number	J:164745
	decreased excitatory postsynaptic current amplitude	J:164745
	fetal growth retardation	J:164745
	hemorrhage	J:164745
	lethality throughout fetal growth and development, incomplete penetrance	J:164745
	normal nervous system phenotype	J:164745
	perinatal lethality, complete penetrance	J:164745
Nedd4tm3.1Bros/Nedd4tm3.1Bros Neurod6tm1(cre)Kan/Neurod6+ involves: 129 * C57BL/6 * C57BL/6N * SJL	abnormal cerebral hemisphere morphology	J:164745
	abnormal dendrite morphology	J:164745
	normal nervous system phenotype	J:164745
	thin cerebral cortex	J:164745