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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Myl3
myosin, light polypeptide 3
MGI:97268
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Tg(Myh6-MYL3*)#Dsc/0
involves: C57BL/6 * SJL
abnormal cardiac muscle tissue morphology J:178377
abnormal myocardial fiber physiology J:195614
abnormal myocardium layer morphology J:195614
cardiac hypertrophy J:178377, J:195614
enlarged heart J:195614
increased heart weight J:178377
thick interventricular septum J:195614
Tg(Myh6-MYL3*A57G)#Dsc/0
involves: C57BL/6 * SJL
abnormal blood circulation J:202154
abnormal cardiac muscle tissue morphology J:178377
abnormal cardiovascular system physiology J:202154
abnormal heart echocardiography feature J:202154
abnormal heart left ventricle morphology J:178377
abnormal myocardial fiber physiology J:178377, J:202154
cardiac hypertrophy J:202154
cardiac interstitial fibrosis J:178377, J:202154
enlarged myocardial fiber J:202154
increased cardiac muscle contractility J:202154
increased cardiac output J:202154
increased cardiac stroke volume J:202154
increased heart weight J:202154
increased left ventricle systolic pressure J:202154
Tg(Myh6-MYL3*E143K)2Dsc/0
Not Specified
abnormal cardiac muscle relaxation J:258831
abnormal cardiovascular system physiology J:258831
abnormal heart echocardiography feature J:258831
abnormal myocardial fiber physiology J:258831
abnormal sarcomere morphology J:258831
abnormal Z line morphology J:258831
absent M line J:258831
cardiac fibrosis J:258831
cardiomyopathy J:258831
decreased cardiac output J:258831
decreased cardiac stroke volume J:258831
decreased heart weight J:258831
increased hydroxyproline level J:258831
small heart J:258831

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory