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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Muc1
mucin 1, transmembrane
MGI:97231
22 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Il10tm1Cgn/Il10tm1Cgn
Tg(MUC1)79.24Gend/0
B6.Cg-Il10tm1Cgn Tg(MUC1)79.24Gend
increased colon adenocarcinoma incidence J:149347
large intestinal inflammation J:149347
rectal prolapse J:149347
Krastm4Tyj/Kras+
Ptf1atm1.1(cre)Cvw/Ptf1a+
Tg(MUC1)79.24Gend/0
B6.Cg-Krastm4Tyj Ptf1atm1.1(cre)Cvw Tg(MUC1)79.24Gend
decreased metastatic potential J:138959
increased pancreas tumor incidence J:138959, J:234412
increased pancreatic ductal adenocarcinoma incidence J:138959
increased pancreatic intraepithelial neoplasia incidence J:138959, J:234412
Krastm4Tyj/Kras+
Tg(MUC1)79.24Gend/0
involves: 129S4/SvJae * C57BL/6
decreased interferon-gamma secretion J:154046
increased IgG level J:154046
increased IgM level J:154046
increased regulatory T cell number J:154046
uterus adenomyosis J:154046
Muc1tm1Gend/Muc1tm1Gend
Tg(WapTgfa)215Bri/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
increased mammary gland tumor incidence J:123146
mammary gland hyperplasia J:123146
normal neoplasm J:123146
Muc1tm1Gend/Muc1tm1Gend
Tg(Wnt1)1Hev/?
involves: FVB
decreased tumor growth/size J:82470
Tg(Ela1-TAg*)79Mjt/0
Tg(MUC1)79.24Gend/0
involves: C57BL/6 * DBA/2
abnormal pancreas morphology J:64570
normal immune system phenotype J:64570
increased pancreas adenoma incidence J:64570
increased pancreas tumor incidence J:64570
increased pancreatic acinar cell carcinoma incidence J:64570
Tg(MUC1)79.24Gend/0
involves: C57BL/6
abnormal humoral immune response J:128899
increased IgG level J:154046
increased IgM level J:154046
increased tumor incidence J:128899

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory