Mep1a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mep1a
meprin 1 alpha
MGI:96963

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mep1a^{tm1a(KOMP)Wtsi}/Mep1a^{tm1a(KOMP)Wtsi} C57BL/6N-Mep1a^{tm1a(KOMP)Wtsi}/Wtsi	abnormal bone structure	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased total body fat amount	J:211773
	increased bone mineral content	J:211773
Mep1a^tm1Bond/Mep1a^tm1Bond involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal blood homeostasis	J:145037
	abnormal blood urea nitrogen level	J:145037
	abnormal body temperature homeostasis	J:145037
	abnormal chemokine level	J:145685
	abnormal circulating creatinine level	J:145037
	abnormal circulating interleukin-1 beta level	J:145037
	abnormal cytokine level	J:145037, J:145685
	abnormal leukocyte physiology	J:145037
	abnormal renal tubule morphology	J:145037
	abnormal renal/urinary system physiology	J:145037
	abnormal tumor necrosis factor level	J:145037
	decreased litter size	J:145685
	increased circulating interleukin-1 beta level	J:145685
	increased circulating interleukin-6 level	J:145685
	increased susceptibility to induced colitis	J:145685
	proximal convoluted tubule brush border loss	J:145037
	urinary bladder inflammation	J:145037

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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