Loricrin Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Loricrin
loricrin cornified envelope precursor protein
MGI:96816

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Loricrin^{tm1.1(KOMP)Vlcg}/Loricrin⁺ C57BL/6N-Loricrin^{tm1.1(KOMP)Vlcg}/Ucd	abnormal heart morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal uterus morphology	J:211773
	abnormal vibrissa morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged uterus	J:211773
	improved glucose tolerance	J:211773
	increased kidney weight	J:211773
	small testis	J:211773
Loricrin^{tm1.1(KOMP)Vlcg}/Loricrin^{tm1.1(KOMP)Vlcg} C57BL/6N-Loricrin^{tm1.1(KOMP)Vlcg}/Ucd	abnormal skin morphology	J:211773
	abnormal testis morphology	J:211773
	increased kidney weight	J:211773
	increased spleen weight	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small testis	J:211773
Loricrin^tm1Der/Loricrin^tm1Der FVB.129S7-Loricrin^tm1Der	abnormal epidermis stratum corneum morphology	J:65187
	abnormal skin condition	J:65187
	decreased body size	J:65187
	decreased skin tensile strength	J:65187
	erythroderma	J:65187
	impaired skin barrier function	J:65187
	translucent skin	J:65187

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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