56 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcna1mceph/Kcna1mceph BALB/cByJ-Kcna1mceph/J	abnormal astrocyte morphology	J:38104
	abnormal brain development	J:38104
	abnormal brain morphology	J:38104, J:119491
	abnormal brain size	J:38104
	abnormal gait	J:38104
	abnormal hearing physiology	J:119491
	abnormal locomotor behavior	J:119491
	abnormal posture	J:38104, J:119491
	abnormal reflex	J:38104
	abnormal sexual interaction	J:38104
	chromodacryorrhea	J:38104
	convulsive seizures	J:89910, J:119491
	decreased body size	J:38104
	ear inflammation	J:119491
	enlarged hippocampus	J:119491
	excessive tearing	J:38104
	eye inflammation	J:119491
	increased brain size	J:38104, J:89909
	increased brain weight	J:38104
	increased startle reflex	J:119491
	seizures	J:89910
	tonic-clonic seizures	J:89910
	tremors	J:119491
Kcna1tm1Jmay/Kcna1+ B6.129S4-Kcna1tm1Jmay	abnormal inhibitory postsynaptic currents	J:82778
	abnormal motor coordination/balance	J:82778
	normal behavior/neurological phenotype	J:82778
Kcna1tm1Jmay/Kcna1tm1Jmay B6.129S4-Kcna1tm1Jmay	embryonic lethality, complete penetrance	J:82778
Kcna1tm1Tem/Kcna1+ involves: 129S7/SvEvBrd * various	increased susceptibility to pharmacologically induced seizures	J:47349
Kcna1tm1Tem/Kcna1tm1Tem C3Fe.129S7-Kcna1tm1Tem	abnormal action potential	J:105296
	abnormal mitochondrial ATP synthesis coupled electron transport	J:206598
	abnormal nervous system electrophysiology	J:105296
	decreased chemical nociceptive threshold	J:107933
	decreased chemically-elicited antinociception	J:107933
	decreased nerve fiber response threshold	J:105296
	decreased paired-pulse ratio	J:206598
	decreased thermal nociceptive threshold	J:107933
	oxidative stress	J:206598
	seizures	J:206598
Kcna1tm1Tem/Kcna1tm1Tem involves: 129S7/SvEvBrd	abnormal cardiovascular system physiology	J:164091
	abnormal impulse conducting system conduction	J:164091
	atrioventricular block	J:164091
	decreased heart rate	J:164091
	myoclonus	J:164091
	postnatal lethality, incomplete penetrance	J:164091
	premature death	J:164091
	seizures	J:164091
	tonic-clonic seizures	J:164091
	ventricular premature beat	J:164091
Kcna1tm1Tem/Kcna1tm1Tem involves: 129S7/SvEvBrd * BALB/cByJ * C3HeB/FeJ	abnormal cerebral cortex morphology	J:119491
	abnormal hearing physiology	J:119491
	abnormal locomotor behavior	J:119491
	abnormal posture	J:119491
	convulsive seizures	J:119491
	ear inflammation	J:119491
	enlarged hippocampus	J:119491
	eye inflammation	J:119491
	increased startle reflex	J:119491
	porphyria	J:119491
	tremors	J:119491
Kcna1tm1Tem/Kcna1tm1Tem involves: 129S7/SvEvBrd * C57BL/6	abnormal PNS synaptic transmission	J:77281
	ataxia	J:77281
	impaired balance	J:77281
	impaired swimming	J:77281
	seizures	J:77281
	tremors	J:77281
Kcna1tm1Tem/Kcna1tm1Tem involves: 129S7/SvEvBrd * various	abnormal action potential	J:47349
	abnormal behavior	J:47349
	abnormal brain wave pattern	J:47349
	abnormal CNS synaptic transmission	J:47349
	abnormal paired-pulse facilitation	J:47349
	increased blinking frequency	J:47349
	increased startle reflex	J:47349
	increased susceptibility to pharmacologically induced seizures	J:47349
	premature death	J:47349
	seizures	J:47349
	tonic-clonic seizures	J:47349