Itga5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itga5
integrin alpha 5 (fibronectin receptor alpha)
MGI:96604

21 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itga5^tm1Hyn/Itga5^tm1Hyn involves: 129S2/SvPas * C57BL/6J	abnormal blood vessel morphology	J:16248
	abnormal dorsal aorta morphology	J:16248
	abnormal embryonic tissue morphology	J:16248
	abnormal extraembryonic mesoderm development	J:16248
	abnormal extraembryonic tissue morphology	J:16248
	abnormal rostral-caudal axis patterning	J:16248
	abnormal vitelline vasculature morphology	J:16248
	caudal body truncation	J:16248
	normal cellular phenotype	J:16248
	decreased paraxial mesoderm size	J:16248
	embryonic growth retardation	J:16248
	embryonic lethality during organogenesis, complete penetrance	J:16248
	incomplete embryo turning	J:16248
	incomplete somite formation	J:16248
	kinked neural tube	J:16248
	short rostral-caudal axis	J:16248
Itga5^tm1Hyn/Itga5^tm2Hyn Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	no abnormal phenotype detected	J:161850
Itga5^tm2.1Hyn/Itga5^tm2.1Hyn involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal blood vessel morphology	J:161850
	embryonic growth retardation	J:161850
	embryonic lethality during organogenesis, complete penetrance	J:161850
	incomplete somite formation	J:161850
Itga5^tm2Hyn/Itga5^tm2Hyn involves: 129S1/Sv * 129X1/SvJ	abnormal cerebral cortex morphology	J:159465
Itga5^tm2Hyn/Itga5^tm2Hyn involves: 129S1/Sv * 129X1/SvJ	abnormal neuronal migration	J:159465
Itga5^tm2Hyn/Itga5^tm2Hyn Tg(Tek-cre)1Ywa/0 B6.Cg-Tg(Tek-cre)1Ywa Itga5^tm2Hyn	patent ductus arteriosus	J:161850
	postnatal lethality, incomplete penetrance	J:161850

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23