Igkc Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Igkc
immunoglobulin kappa constant
MGI:96495

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Igkc^tm1Bgmn/Igkc^tm1Bgmn involves: 129P2/OlaHsd	abnormal B cell number	J:28868, J:118712
	abnormal humoral immune response	J:28868
	abnormal Peyer's patch germinal center morphology	J:28868
	abnormal Peyer's patch morphology	J:28868
Igkc^tm1Cgn/Igkc⁺ involves: C57BL/6	increased mature B cell number	J:64287
Igkc^tm1Cgn/Igkc^tm1Cgn involves: C57BL/6	abnormal B cell differentiation	J:64287
	decreased mature B cell number	J:64287
	increased immature B cell number	J:64287
	increased mature B cell number	J:64287
	spleen hypoplasia	J:64287
Igkc^tm1Jkbv/Igkc^tm1Jkbv Not Specified	abnormal B cell differentiation	J:137738
	abnormal immunoglobulin level	J:137738
	abnormal immunoglobulin light chain V-J recombination	J:137738
	decreased immature B cell number	J:137738
	decreased mature B cell number	J:137738
	increased pre-B cell number	J:137738

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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