Ighg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ighg1
immunoglobulin heavy constant gamma 1 (G1m marker)
MGI:96446

20 phenotypes from 7 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ighg1^em1Wliu/Ighg1^em1Wliu C57BL/6-Ighg1^em1Wliu	abnormal plasma cell differentiation	J:266937
	enhanced humoral immune response	J:266937
	increased anti-double stranded DNA antibody level	J:266937
	increased anti-nuclear antigen antibody level	J:266937
	increased autoantibody level	J:266937
	increased germinal center B cell number	J:266937
	increased IgG1 level	J:266937
	increased plasma cell number	J:266937
Ighg1^tm1.1Ksho/Ighg1⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:39568
Ighg1^tm1.1Ksho/Ighg1⁺ involves: 129P2/OlaHsd * C57BL/6	decreased IgG1 level	J:39568
Ighg1^tm1.1Ksho/Ighg1^tm1.1Ksho involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:39568
	decreased IgG1 level	J:39568
Ighg1^tm1.1Pyu/Ighg1⁺ B6.C(Cg)-Ighg1^tm1.1Pyu	decreased body temperature	J:198154
	decreased IgG1 level	J:198154
	decreased IgG2c level	J:198154
	normal immune system phenotype	J:198154
	increased IgE level	J:198154
	increased IgG2a level	J:198154
	increased susceptibility to type I hypersensitivity reaction	J:198154
Ighg1^tm1.1Pyu/Ighg1^tm1.1Pyu B6.C(Cg)-Ighg1^tm1.1Pyu	decreased body temperature	J:198154
	decreased IgG1 level	J:198154
	decreased IgG2c level	J:198154
	normal immune system phenotype	J:198154
	increased IgE level	J:198154
	increased IgG2a level	J:198154
	increased IgG2b level	J:198154
	increased susceptibility to type I hypersensitivity reaction	J:198154
	increased susceptibility to xenobiotic induced morbidity/mortality	J:198154
Ighg1^tm1Ksho/Ighg1⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:39568
Ighg1^tm1Ksho/Ighg1⁺ involves: 129P2/OlaHsd * C57BL/6	decreased IgG1 level	J:39568
Ighg1^tm1Ksho/Ighg1^tm1Ksho involves: 129P2/OlaHsd * C57BL/6	abnormal B cell physiology	J:39568
	absent memory B cells	J:39568
	decreased IgG1 level	J:39568
Ighg1^tm2Cgn/Ighg1⁺ (C57BL/6 x 129P2/OlaHsd)F1	abnormal class switch recombination	J:146428
Ighg1^tm2Cgn/Ighg1⁺ (C57BL/6 x 129P2/OlaHsd)F1	decreased IgG1 level	J:146428
Ighg1^tm3Cgn/Ighg1⁺ involves: 129P2/OlaHsd * BALB/c * C57BL/6	abnormal class switch recombination	J:166887
	decreased IgG1 level	J:166887
Ighg1^tm4Cgn/Ighg1^tm4Cgn involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:166887

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