H2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2
histocompatibility-2, MHC
MGI:95894

23 phenotypes from 9 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
H2^b/H2^b NOD.B10SnJ-H2^b	decreased physiological sensitivity to xenobiotic	J:14178
	decreased susceptibility to autoimmune diabetes	J:14178
	periinsulitis	J:14178
H2^b/H2^d (C57BL/6 x DBA/2)F1	abnormal cytokine secretion	J:106141
	abnormal liver physiology	J:106141
	abnormal T cell differentiation	J:106141
	decreased hematocrit	J:106141
	decreased susceptibility to parasitic infection	J:106141
	increased autoantibody level	J:106141
H2^b/H2^g7 NOD.B10SnJ-H2^b	decreased susceptibility to autoimmune diabetes	J:14178
H2^d/H2^d DBA/2	abnormal cytokine secretion	J:106141
	abnormal liver physiology	J:106141
	abnormal T cell differentiation	J:106141
	decreased hematocrit	J:106141
	decreased susceptibility to parasitic infection	J:106141
	increased autoantibody level	J:106141
H2^dlAb1-Ea/H2^dlAb1-Ea B6.129S2-H2^dlAb1-Ea/J	increased susceptibility to bacterial infection	J:123934
H2^dlAb1-Ea/H2^dlAb1-Ea B6.129S2-H2^dlAb1-Ea/J	increased susceptibility to induced morbidity/mortality	J:123934
H2^dlAb1-Ea/H2^dlAb1-Ea involves: 129S2/SvPas * C57BL/6	abnormal immunoglobulin level	J:57484
	abnormal T cell number	J:57484
	decreased CD4-positive, alpha-beta T cell number	J:57484
	decreased IgG1 level	J:57484
	decreased IgG2a level	J:57484
	normal immune system phenotype	J:157516
	increased CD8-positive, alpha-beta T cell number	J:57484
	increased IgM level	J:57484
H2^h2/H2^g7 NOD.Cg-H2^h2	decreased susceptibility to autoimmune diabetes	J:14178
H2^h2/H2^h2 NOD.Cg-H2^h2	decreased physiological sensitivity to xenobiotic	J:14178
	decreased susceptibility to autoimmune diabetes	J:14178
	insulitis	J:14178
	periinsulitis	J:14178
H2^h4/H2^g7 NOD.Cg-H2^h4	decreased susceptibility to autoimmune diabetes	J:14178
H2^h4/H2^h4 NOD.Cg-H2^h4	abnormal cytokine secretion	J:54563
	decreased physiological sensitivity to xenobiotic	J:14178
	decreased susceptibility to autoimmune diabetes	J:14178
	insulitis	J:14178
	periinsulitis	J:14178
	thyroid gland inflammation	J:54563
H2ⁱ⁵/H2^g7 NOD.Cg-H2ⁱ⁵	decreased susceptibility to autoimmune diabetes	J:14178
H2ⁱ⁵/H2ⁱ⁵ NOD.Cg-H2ⁱ⁵	decreased physiological sensitivity to xenobiotic	J:14178
	decreased susceptibility to autoimmune diabetes	J:14178
	periinsulitis	J:14178
H2ⁱ⁷/H2^g7 (NOD x NOD.Cg-H2ⁱ⁷)F1	insulitis	J:14178
H2ⁱ⁷/H2^g7 NOD.Cg-H2ⁱ⁷	decreased susceptibility to autoimmune diabetes	J:14178
H2ⁱ⁷/H2ⁱ⁷ NOD.Cg-H2ⁱ⁷	decreased physiological sensitivity to xenobiotic	J:14178
	decreased susceptibility to autoimmune diabetes	J:14178
	periinsulitis	J:14178
H2^k/H2^g7 NOD.Cg-H2^k	decreased susceptibility to autoimmune diabetes	J:14178
H2^k/H2^k NOD.Cg-H2^k	increased physiological sensitivity to xenobiotic	J:14178
	increased susceptibility to autoimmune diabetes	J:14178
	periinsulitis	J:14178

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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