28 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Folr1tm1.1(KOMP)Vlcg/Folr1+ C57BL/6N-Folr1tm1.1(KOMP)Vlcg/Tcp	abnormal cholesterol homeostasis	J:211773
	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	enlarged heart	J:211773
	increased circulating alanine transaminase level	J:211773
	increased heart atrium size	J:211773
	small testis	J:211773
Folr1tm1.1(KOMP)Vlcg/Folr1tm1.1(KOMP)Vlcg C57BL/6N-Folr1tm1.1(KOMP)Vlcg/Tcp	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Folr1tm1Fnn/Folr1+ involves: 129 * C57BL/6J	abnormal crypts of Lieberkuhn morphology	J:96380
	abnormal folic acid level	J:96380
	increased incidence of tumors by chemical induction	J:96380
	increased physiological sensitivity to xenobiotic	J:96380
Folr1tm1Fnn/Folr1+ involves: 129P2/OlaHsd * C57BL/6J	increased circulating homocysteine level	J:57765
Folr1tm1Fnn/Folr1tm1Fnn involves: 129 * C57BL/6J	abnormal folic acid level	J:96380
Folr1tm1Fnn/Folr1tm1Fnn involves: 129P2/OlaHsd * C57BL/6J	abnormal embryonic neuroepithelial layer differentiation	J:57765
	abnormal neural crest cell migration	J:57765
	abnormal otic pit morphology	J:57765
	absent first pharyngeal arch	J:57765
	absent forebrain	J:57765
	absent optic vesicle	J:57765
	absent trigeminal ganglion	J:57765
	decreased embryonic neuroepithelium thickness	J:57765
	delayed rostral neuropore closure	J:57765
	embryonic growth retardation	J:57765
	embryonic lethality during organogenesis, complete penetrance	J:57765
	incomplete embryo turning	J:57765
	incomplete rostral neuropore closure	J:57765
	incomplete somite formation	J:57765