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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Flt1
FMS-like tyrosine kinase 1
MGI:95558
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Akt1tm1Mbb/Akt1+
Flt1tm1Jrt/Flt1+
involves: 129P2/OlaHsd 		normal cardiovascular system phenotype J:151369
Dmdmdx-5Cv/Dmdmdx-5Cv
Flt1tm1Jrt/Flt1+
involves: C3HA * C57BL/6Ros 		abnormal blood circulation J:164891
abnormal muscle contractility J:164891
abnormal muscle development J:164891
abnormal skeletal muscle fiber morphology J:164891
abnormal skeletal muscle fiber size J:164891
increased capillary density J:164891
increased satellite cell number J:164891
normal muscle phenotype J:164891
Dmdmdx-5Cv/Dmdmdx-5Cv
Flt1tm1Jrt/Flt1+
Utrntm1Jrs/Utrntm1Jrs
involves: 129S1/Sv * 129X1/SvJ * C3HA * C57BL/6Ros 		centrally nucleated skeletal muscle fibers J:164891
extended life span J:164891
increased body weight J:164891
Flt1tm1.1Fong/Flt1tm1.1Fong
Kdrtm1Jrt/Kdr+
Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
involves: 129 * C57BL/6NCr * CD-1 		increased angiogenesis J:202202
Flt1tm2Msh/Flt1tm2Msh
Kdrtm1Jrt/Kdr+
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal vascular endothelial cell differentiation J:95387
abnormal vascular endothelial cell migration J:95387
prenatal lethality, incomplete penetrance J:95387
Flt1tm2Msh/Flt1tm2Msh
Kdrtm1Jrt/Kdrtm1Jrt
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal vascular endothelial cell migration J:95387
prenatal lethality J:95387
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory