Fgr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgr
FGR proto-oncogene, Src family tyrosine kinase
MGI:95527

19 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgr^Mhdaali18/Fgr⁺ C3HeB/FeJ-Fgr^Mhdaali18	abnormal digit morphology	J:112868
	abnormal foot pad morphology	J:112868
	dermatitis	J:112868
	increased inflammatory response	J:112868
Fgr^Mhdaali18/Fgr⁺ either: (involves: BALB/c * C3HeB/FeJ) or (involves: C3HeB/FeJ * C57BL/6J) or (involves: C3HeB/FeJ * CAST/EiJ)	normal limbs/digits/tail phenotype	J:112868
Fgr^Mhdaali18/Fgr^Mhdaali18 C3HeB/FeJ-Fgr^Mhdaali18	abnormal bone marrow cavity morphology	J:112868
	abnormal digit morphology	J:112868
	abnormal foot pad morphology	J:112868
	abnormal joint morphology	J:112868
	abnormal metacarpal bone morphology	J:112868
	abnormal metatarsal bone morphology	J:112868
	abnormal phalanx morphology	J:112868
	abnormal tail morphology	J:112868
	arthritis	J:112868
	decreased bone mineral content	J:112868
	decreased bone mineral density	J:112868
	decreased compact bone area	J:112868
	dermatitis	J:112868
	skin hemorrhage	J:112868
Fgr^Mhdaali18/Fgr^Mhdaali18 involves: C3HeB/FeJ * C57BL/6J	abnormal foot pad morphology	J:112868
Fgr^tm1Hev/Fgr^tm1Hev B6.129S7-Fgr^tm1Hev	abnormal inflammatory response	J:113463
Fgr^tm1Hev/Fgr^tm1Hev involves: 129S7/SvEvBrd * C57BL/6	abnormal interferon-gamma secretion	J:131738
Fgr^tm2Hev/Fgr^tm2Hev involves: 129S7/SvEvBrd * C57BL/6J	no abnormal phenotype detected	J:16994

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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