Fah Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fah
fumarylacetoacetate hydrolase
MGI:95482

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn1a^tm1Tyj/Cdkn1a^tm1Tyj Fah^tm1Mgo/Fah^tm1Mgo involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6	abnormal hepatocyte morphology	J:138701
	abnormal liver physiology	J:138701
	dilated proximal convoluted tubule	J:138701
	increased hepatocellular carcinoma incidence	J:138701
	increased hepatocyte apoptosis	J:138701
	increased hepatocyte proliferation	J:138701
	increased renal carcinoma incidence	J:138701
	kidney cyst	J:138701
	normal mortality/aging	J:138701
	weight loss	J:138701
Fah^tm1Mgo/Fah^tm1Mgo Hgd^aku/Hgd⁺ involves: 129S7/SvEvBrd * NB	abnormal hepatocyte morphology	J:77295
	abnormal liver morphology	J:77295
	abnormal liver physiology	J:77295
	dilated renal tubule	J:77295
	increased circulating tyrosine level	J:77295
	jaundice	J:77295
	kidney inflammation	J:77295
	pale liver	J:77295
	weight loss	J:77295
Fah^tm1Mgo/Fah^tm1Mgo Hgd^aku/Hgd^aku involves: 129S7/SvEvBrd * NB	normal homeostasis/metabolism phenotype	J:77295
	normal liver/biliary system phenotype	J:77295
	normal renal/urinary system phenotype	J:77295

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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