Fabp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fabp3
fatty acid binding protein 3, muscle and heart
MGI:95476

27 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fabp3^Gt(XE705)Byg/Fabp3^Gt(XE705)Byg involves: 129P2/OlaHsd * C57BL/6J	abnormal brown adipose tissue morphology	J:167535
	abnormal brown adipose tissue physiology	J:167535
	abnormal free fatty acids level	J:167535
	abnormal glucose homeostasis	J:167535
	abnormal lipid homeostasis	J:167535
	abnormal triglyceride level	J:167535
	decreased brown adipose tissue amount	J:167535
	decreased circulating glucose level	J:167535
	decreased fatty acids level	J:167535
	decreased liver glycogen level	J:167535
	decreased triglyceride level	J:167535
	impaired adaptive thermogenesis	J:167535
	increased circulating free fatty acids level	J:167535
	increased circulating triglyceride level	J:167535
	increased fatty acids level	J:167535
	increased oxygen consumption	J:167535
	increased respiratory quotient	J:167535
	increased triglyceride level	J:167535
Fabp3^{tm1a(EUCOMM)Wtsi}/Fabp3⁺ C57BL/6N-Fabp3^{tm1a(EUCOMM)Wtsi}/Ics	abnormal lens morphology	J:165965
	cataract	J:165965
Fabp3^tm1Bin/Fabp3^tm1Bin involves: 129P2/OlaHsd * BALB/c	abnormal lipid homeostasis	J:54614
	cardiac hypertrophy	J:54614
	fatigue	J:54614
	hypoglycemia	J:54614
	increased cardiac muscle cell glucose uptake	J:54614
	increased circulating free fatty acids level	J:54614
	increased heart weight	J:54614
	increased susceptibility to induced morbidity/mortality	J:54614
Fabp3^tm1Jshr/Fabp3⁺ B6.129-Fabp3^tm1Jshr	decreased circulating glucose level	J:102858
Fabp3^tm1Jshr/Fabp3⁺ B6.129-Fabp3^tm1Jshr	increased insulin sensitivity	J:102858

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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