Zfp521 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zfp521
zinc finger protein 521
MGI:95459

49 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Emu-Zfp521)1Homy/0 Not Specified	abnormal B cell differentiation	J:160392
	normal hematopoietic system phenotype	J:160392
	increased B cell number	J:160392
	normal neoplasm	J:160392
Zfp521^tm1Ngc/Zfp521^tm1Ngc Tg(Col2a1-cre)#Amc/0 Not Specified	abnormal bone mineralization	J:166058
	abnormal bone structure	J:166058
	abnormal chondrocyte physiology	J:166058, J:175572
	abnormal long bone epiphyseal plate morphology	J:166058
	abnormal long bone epiphyseal plate proliferative zone	J:166058
	decreased length of long bones	J:166058, J:175572
	decreased long bone epiphyseal plate size	J:166058
	decreased width of hypertrophic chondrocyte zone	J:166058
	postnatal growth retardation	J:166058, J:175572
	proportional dwarf	J:166058
	small thoracic cage	J:166058
	small vertebrae	J:166058
Zfp521^tm1Nohk/Zfp521⁺ involves: C57BL/6J	no abnormal phenotype detected	J:214267
Zfp521^tm1Nohk/Zfp521^tm1Nohk B6J.Cg-Zfp521^tm1Nohk	abnormal cerebellum morphology	J:214267
	abnormal dentate gyrus morphology	J:214267
	abnormal hippocampus development	J:214267
	abnormal hippocampus granule cell morphology	J:214267
	abnormal hippocampus morphology	J:214267
	abnormal hippocampus neuron morphology	J:214267
	abnormal impulsive behavior control	J:214267
	abnormal learning/memory/conditioning	J:214267
	abnormal neuronal stem cell physiology	J:214267
	abnormal resting posture	J:214267
	abnormal social investigation	J:214267
	decreased adrenal gland weight	J:214267
	decreased anxiety-related response	J:214267
	decreased body size	J:214267
	decreased body weight	J:214267
	decreased brain size	J:214267
	decreased brain weight	J:214267
	decreased heart weight	J:214267
	decreased kidney weight	J:214267
	decreased liver weight	J:214267
	decreased long bone epiphyseal plate size	J:214267
	decreased lung weight	J:214267
	decreased neuronal precursor cell number	J:214267
	decreased pituitary gland weight	J:214267
	decreased prepulse inhibition	J:214267
	decreased spleen weight	J:214267
	decreased thymus weight	J:214267
	impaired neuron differentiation	J:214267
	increased coping response	J:214267
	increased locomotor activity	J:214267
	postnatal growth retardation	J:214267
	premature death	J:214267
Zfp521^tm2Ngc/Zfp521⁺ Not Specified	abnormal clavicle morphology	J:167992
Zfp521^tm2Ngc/Zfp521⁺ Not Specified	increased hyoid bone size	J:167992

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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