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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Acadvl
acyl-Coenzyme A dehydrogenase, very long chain
MGI:895149
36 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Acadvltm1Uab/Acadvltm1Uab
involves: 129S6/SvEvTac * C57BL/6
abnormal enzyme/coenzyme activity J:72193
abnormal heart morphology J:72193
abnormal lipid homeostasis J:72193
hepatic steatosis J:72193
increased circulating carnitine level J:72193
Acadvltm1Vje/Acadvl+
involves: 129/Sv * C57BL/6
abnormal amino acid level J:102010
Acadvltm1Vje/Acadvltm1Vje
involves: 129/Sv * Black Swiss * C57BL/6
abnormal adipose tissue physiology J:106714
abnormal amino acid level J:106714
abnormal brown adipose tissue morphology J:106714
abnormal cellular respiration J:106714
abnormal myocardial fiber morphology J:106714
decreased glycogen level J:106714
decreased heart rate J:106714
hepatic steatosis J:106714
hypoglycemia J:106714
impaired adaptive thermogenesis J:106714
increased sensitivity to induced morbidity/mortality J:106714
Acadvltm1Vje/Acadvltm1Vje
involves: 129/Sv * C57BL/6
abnormal adipose tissue morphology J:102010
abnormal amino acid level J:102010
abnormal myocardial fiber morphology J:98627
abnormal skeletal muscle fiber morphology J:98627
cardiomyopathy J:98627
fatigue J:102010
impaired adaptive thermogenesis J:102010
impaired glucose tolerance J:102010
increased body weight J:102010
increased sensitivity to induced morbidity/mortality J:102010
increased tumor incidence J:102010
irregular heartbeat J:98627
myocardial fiber degeneration J:98627
premature death J:102010
Acadvltm1Zkhu/Acadvltm1Zkhu
Tg(Myh6-cre)1Jmk/0
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr
abnormal adaptive thermogenesis J:208711
abnormal cardiovascular system physiology J:208711
abnormal heart left ventricle morphology J:208711
abnormal heart morphology J:208711
abnormal myocardial fiber morphology J:208711
decreased circulating glucose level J:208711
decreased core body temperature J:208711
decreased heart rate J:208711
decreased respiratory quotient J:208711
decreased ventricle muscle contractility J:208711
dilated cardiomyopathy J:208711
dilated heart left ventricle J:208711
increased heart weight J:208711
increased sensitivity to induced morbidity/mortality J:208711
lethargy J:208711

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory