Ranbp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ranbp2
RAN binding protein 2
MGI:894323

25 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ranbp2^{Gt(pGT0pfs)630Wcs}/Ranbp2⁺ 129P2/OlaHsd-Ranbp2^{Gt(pGT0pfs)630Wcs}	abnormal nervous system physiology	J:116134
	abnormal rod electrophysiology	J:116134
	decreased susceptibility to diet-induced obesity	J:116134
	impaired glucose tolerance	J:116134
Ranbp2^{Gt(pGT0pfs)630Wcs}/Ranbp2⁺ involves: 129P2/OlaHsd * C57BL/6J	normal growth/size/body region phenotype	J:116134
	normal homeostasis/metabolism phenotype	J:116134
	normal nervous system phenotype	J:116134
Ranbp2^{Gt(pGT0pfs)630Wcs}/Ranbp2^{Gt(pGT0pfs)630Wcs} either: 129P2/OlaHsd-Ranbp2^{Gt(pGT0pfs)630Wcs} or (involves: 129P2/OlaHsd * C57BL/6J)	prenatal lethality, complete penetrance	J:116134
Ranbp2^{tm1.1(KOMP)Vlcg}/Ranbp2⁺ C57BL/6N-Ranbp2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal epididymis morphology	J:211773
	abnormal testis morphology	J:211773
	enlarged epididymis	J:211773
	small testis	J:211773
Ranbp2^{tm1.1(KOMP)Vlcg}/Ranbp2^{tm1.1(KOMP)Vlcg} C57BL/6N-Ranbp2^{tm1.1(KOMP)Vlcg}/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
Ranbp2^{tm1.1(KOMP)Vlcg}/Ranbp2^{tm1.1(KOMP)Vlcg} C57BL/6N-Ranbp2^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Ranbp2^tm1.1Jvd/Ranbp2⁺ involves: 129/Sv * C57BL/6	aneuploidy	J:137482
Ranbp2^tm1.1Jvd/Ranbp2^tm1.1Jvd involves: 129/Sv * C57BL/6	embryonic lethality, complete penetrance	J:137482
Ranbp2^tm1Jvd/Ranbp2^tm1.1Jvd involves: 129/Sv * C57BL/6	abnormal mitosis	J:137482
	aneuploidy	J:137482
	decreased tumor latency	J:137482
	elevated level of mitotic sister chromatid exchange	J:137482
	increased hepatocellular carcinoma incidence	J:137482
	increased incidence of tumors by chemical induction	J:137482
	increased lung carcinoma incidence	J:137482
	increased sarcoma incidence	J:137482
	increased tumor incidence	J:137482
Ranbp2^tm1Jvd/Ranbp2^tm1Jvd involves: 129/Sv * C57BL/6	abnormal mitosis	J:137482
	aneuploidy	J:137482
	decreased tumor latency	J:137482
	elevated level of mitotic sister chromatid exchange	J:137482
	increased hepatocellular carcinoma incidence	J:137482
	increased incidence of tumors by chemical induction	J:137482
	increased lung carcinoma incidence	J:137482
	increased sarcoma incidence	J:137482
	increased tumor incidence	J:137482

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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