Cyp19a1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
MGI:88587

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Cyp19a1^tm1Esi/Cyp19a1^tm1Esi involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal aorta bulb morphology	J:184647
	abnormal gonadal fat pad morphology	J:184647
	abnormal liver morphology	J:184647
	atherosclerotic lesions	J:184647
	decreased circulating HDL cholesterol level	J:184647
	decreased circulating insulin level	J:184647
	hypertension	J:184647
	impaired glucose tolerance	J:184647
	increased body weight	J:184647
	increased circulating C-reactive protein level	J:184647
	increased circulating cholesterol level	J:184647
	increased circulating glucose level	J:184647
	increased circulating interleukin-6 level	J:184647
	increased circulating LDL cholesterol level	J:184647
	increased circulating triglyceride level	J:184647
	increased circulating tumor necrosis factor level	J:184647
	increased circulating VLDL cholesterol level	J:184647
	increased fat cell size	J:184647
	increased liver weight	J:184647
	increased susceptibility to age-related hepatic steatosis	J:184647
	increased systemic arterial blood pressure	J:184647
	insulin resistance	J:184647

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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