Cd5 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd5
CD5 antigen
MGI:88340

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd5^tm1.1Chra/Cd5^tm1.1Chra Tg(Tcra2D2,Tcrb2D2)1Kuch/0 involves: C57BL/6 * FVB/N	decreased interferon-gamma secretion	J:189919
	decreased interleukin-2 secretion	J:189919
	decreased T cell proliferation	J:189919
	decreased T helper 1 cell number	J:189919
	increased interferon-gamma secretion	J:189919
	increased interleukin-6 secretion	J:189919
	increased interleukin-17 secretion	J:189919
Cd28^tm1Mak/Cd28⁺ Cd5^tm1Cgn/Cd5^tm1Cgn either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)	abnormal T cell clonal deletion	J:110925
Cd28^tm1Mak/Cd28^tm1Mak Cd5^tm1Cgn/Cd5⁺ either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)	abnormal T cell clonal deletion	J:110925
Cd28^tm1Mak/Cd28^tm1Mak Cd5^tm1Cgn/Cd5^tm1Cgn either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)	abnormal T cell clonal deletion	J:110925
	increased CD4-positive, alpha-beta T cell number	J:110925
	increased CD8-positive, alpha-beta T cell number	J:110925

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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