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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cd27
CD27 antigen
MGI:88326
18 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd27em1(IMPC)Ccpcz/Cd27em1(IMPC)Ccpcz
C57BL/6NCrl-Cd27em1(IMPC)Ccpcz/Ccpcz 		abnormal digit morphology J:211773
abnormal heart morphology J:211773
abnormal seminal vesicle morphology J:211773
abnormal spleen morphology J:211773
abnormal testis morphology J:211773
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:211773
enlarged heart J:211773
increased prepulse inhibition J:211773
small seminal vesicle J:211773
small testis J:211773
Cd27tm1Jbo/Cd27tm1Jbo
B6.129P2-Cd27tm1Jbo 		abnormal leukopoiesis J:97606
decreased regulatory T cell number J:198200
normal immune system phenotype J:198200
increased leukocyte cell number J:97606
increased T cell apoptosis J:198200
Cd27tm1Jbo/Cd27tm1Jbo
either: B6.129P2-CD27tm1Jbo or 129P2/OlaHsd-Tnfrsf7tm1Jbo 		abnormal CD4-positive, alpha-beta T cell physiology J:65516
abnormal cytotoxic T cell physiology J:65516
abnormal T cell physiology J:65516
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory