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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Grk2
G protein-coupled receptor kinase 2
MGI:87940
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Csrp3tm1Crni/Csrp3tm1Crni
Tg(Myh6-ADRBK1)27Wjk/0
involves: C57BL/6 * SJL
cardiac interstitial fibrosis J:48062
normal cardiovascular system phenotype J:48062, J:66250
decreased ventricle muscle contractility J:48062
Tg(Myh6*)140Lnwd/0
Tg(Myh6-ADRBK1)27Wjk/0
involves: C57BL/6 * CBA * SJL
cardiac hypertrophy J:134706
Tg(Myh6-ADRBK1)12Wjk/?
involves: C57BL/6 * SJL
abnormal heart rate J:37034
increased left ventricle diastolic pressure J:37034, J:127858
Tg(Myh6-ADRBK1)12Wjk/0
Tg(Myh6-ADRBK1)27Wjk/0
involves: C57BL/6 * SJL
normal cardiovascular system phenotype J:127858
Tg(Myh6-ADRBK1)27Wjk/0
involves: C57BL/6 * SJL
increased cardiac muscle contractility J:134706
increased left ventricle diastolic pressure J:37034, J:127858
increased left ventricle systolic pressure J:37034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory