Chrnb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrnb2
cholinergic receptor nicotinic beta 2 subunit
MGI:87891

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chrna7^tm1Bay/Chrna7^tm1Bay Chrnb2^tm1Mdb/Chrnb2^tm1Mdb involves: 129S7/SvEvBrd * C57BL/6J	normal behavior/neurological phenotype	J:94667
	decreased anxiety-related response	J:94667
	enhanced coordination	J:94667
	hyperactivity	J:94667
	impaired passive avoidance behavior	J:94667
Chrnb2^tm1Mdb/Chrnb2^tm1Mdb Chrnb4^tm1Mdb/Chrnb4^tm1Mdb involves: 129S7/SvEvBrd * C57BL/6J	abnormal autonomic nervous system physiology	J:73590
	abnormal single cell response	J:73590
	abnormal urinary bladder physiology	J:73590, J:102601
	abnormal urinary bladder urothelium morphology	J:73590
	cystolithiasis	J:73590
	delayed ear emergence	J:73590
	delayed hair appearance	J:73590
	distended urinary bladder	J:73590
	eyelids fail to open	J:73590
	normal homeostasis/metabolism phenotype	J:73590
	impaired pupillary reflex	J:73590
	increased susceptibility to bacterial infection	J:73590
	intestinal hypoperistalsis	J:73590
	normal muscle phenotype	J:73590
	mydriasis	J:73590
	narrow eye opening	J:73590
	postnatal growth retardation	J:73590
	postnatal lethality, complete penetrance	J:73590
	urinary bladder inflammation	J:73590
	urinary incontinence	J:73590

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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