Aktip Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aktip
AKT interacting protein
MGI:3693832

27 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aktip^{tm1a(EUCOMM)Hmgu}/Aktip^{tm1a(EUCOMM)Hmgu} C57BL/6N-Aktip^{tm1a(EUCOMM)Hmgu}	abnormal craniofacial morphology	J:276210
	abnormal heart morphology	J:276210
	abnormal skeleton morphology	J:276210
	abnormal trabecular bone morphology	J:276210
	abnormal vertebral epiphyseal plate morphology	J:276210
	decreased body weight	J:276210
	decreased bone mineral density	J:276210
	decreased fibroblast proliferation	J:276210
	decreased long bone epiphyseal plate size	J:276210
	decreased subcutaneous adipose tissue amount	J:276210
	decreased total body fat amount	J:276210
	increased cellular sensitivity to DNA damaging agents	J:276210
	increased cellular sensitivity to hydroxyurea	J:276210
	kyphosis	J:276210
	male infertility	J:276210
	normal neoplasm	J:276210
	postnatal lethality	J:276210
	premature death	J:276210
	short femur	J:276210
	short tibia	J:276210
	normal skeleton phenotype	J:276210
	small caudal vertebrae	J:276210
	small heart	J:276210
Aktip^{tm1b(EUCOMM)Hmgu}/Aktip^{tm1b(EUCOMM)Hmgu} C57BL/6N-Aktip^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal retina morphology	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	hyperactivity	J:211773
	increased circulating aspartate transaminase level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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