Zscan10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zscan10
zinc finger and SCAN domain containing 10
MGI:3040700

44 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Zscan10^{Gt(285B6)1.1Cmhd}/Zscan10^{Gt(285B6)1.1Cmhd} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	abnormal heart left ventricle morphology	J:221010
	abnormal IgG level	J:221010
	abnormal lens morphology	J:221010
	abnormal T cell subpopulation ratio	J:221010
	abnormal vision	J:221010
	cataract	J:221010
	decreased body temperature	J:221010
	decreased body weight	J:221010
	decreased bone mass	J:221010
	decreased bone mineral content	J:221010
	decreased circulating calcium level	J:221010
	decreased circulating chloride level	J:221010
	decreased circulating corticosterone level	J:221010
	decreased circulating serum albumin level	J:221010
	decreased heart rate	J:221010
	decreased heart weight	J:221010
	decreased locomotor activity	J:221010
	decreased lung compliance	J:221010
	decreased pulmonary respiratory rate	J:221010
	decreased spleen weight	J:221010
	decreased T cell number	J:221010
	decreased tidal volume	J:221010
	impaired coordination	J:221010
	increased B cell number	J:221010
	increased blood urea nitrogen level	J:221010
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:221010
	increased circulating creatinine level	J:221010
	increased circulating lactate dehydrogenase level	J:221010
	increased IgG1 level	J:221010
	increased IgG2b level	J:221010
	increased liver weight	J:221010
	increased locomotor activity	J:221010
	increased mature NK cell number	J:221010
	increased mean platelet volume	J:221010
	increased prepulse inhibition	J:221010
	increased startle reflex	J:221010
	increased urination frequency	J:221010
	maternal effect	J:221010
	microphthalmia	J:221010
	reduced female fertility	J:221010
	short tibia	J:221010
	thrombocytopenia	J:221010
Zscan10^{tm2a(EUCOMM)Wtsi}/Zscan10⁺ C57BL/6N-Zscan10^{tm2a(EUCOMM)Wtsi}/Wtsi	abnormal retina morphology	J:211773
Zscan10^{tm2a(EUCOMM)Wtsi}/Zscan10^{tm2a(EUCOMM)Wtsi} C57BL/6N-Zscan10^{tm2a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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