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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
MGI:3039603
22 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background
Annotated Term Reference
B3gnt6tm1Lx/B3gnt6tm1Lx
involves: 129S1/Sv * C57BL/6J
abnormal crypts of Lieberkuhn morphology J:123826
abnormal enterocyte proliferation J:123826
abnormal intestinal mucosa morphology J:123826
decreased colon length J:123826
diarrhea J:123826
increased adenocarcinoma incidence J:123826
increased carcinoma incidence J:123826
increased gastrointestinal tumor incidence J:123826
increased incidence of tumors by chemical induction J:123826
increased interferon-gamma secretion J:123826
increased interleukin-2 secretion J:123826
increased intestinal adenoma incidence J:123826
increased macrophage cell number J:123826
increased monocyte cell number J:123826
increased sensitivity to xenobiotic induced morbidity/mortality J:123826
increased susceptibility to induced colitis J:123826
increased susceptibility to weight loss J:123826
increased T cell number J:123826
increased tumor growth/size J:123826
increased tumor necrosis factor secretion J:123826
intestinal ulcer J:123826
rectal hemorrhage J:123826

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory