About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Npc1l1
NPC1 like intracellular cholesterol transporter 1
MGI:2685089
15 phenotypes from 3 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Npc1l1tm1a(EUCOMM)Hmgu/Npc1l1tm1a(EUCOMM)Hmgu
involves: C57BL/6 * C57BL/6N 		abnormal intestinal cholesterol absorption J:226578
decreased circulating cholesterol level J:226578
Npc1l1tm1a(EUCOMM)Hmgu/Npc1l1tm1a(EUCOMM)Hmgu
involves: C57BL/6N 		decreased intestinal cholesterol absorption J:263730
Npc1l1tm1Swa/Npc1l1tm1Swa
involves: 129P2/OlaHsd * C57BL/6 		abnormal cholesterol level J:89712
decreased intestinal cholesterol absorption J:89712
Npc1l1tm1Yaio/Npc1l1tm1Yaio
C57BL/6-Npc1l1tm1Yaio 		abnormal cholesterol homeostasis J:98568
abnormal circulating LDL cholesterol level J:98568
abnormal gallbladder physiology J:98568
abnormal intestinal lipid absorption J:98568
abnormal lipid homeostasis J:98568
abnormal triglyceride level J:98568
decreased circulating cholesterol level J:98568
decreased circulating glucose level J:98568
decreased circulating HDL cholesterol level J:98568
decreased intestinal cholesterol absorption J:98568
decreased susceptibility to diet-induced hepatic steatosis J:98568
decreased susceptibility to diet-induced obesity J:98568
decreased susceptibility to hyperlipidemia J:98568
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory