Ric8b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ric8b
RIC8 guanine nucleotide exchange factor B
MGI:2682307

16 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Omp^tm4(cre)Mom/Omp⁺ Ric8b^{tm1c(EUCOMM)Hmgu}/Ric8b^{tm1c(EUCOMM)Hmgu} involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL	abnormal olfactory bulb glomerular layer morphology	J:247954
	abnormal olfactory epithelium physiology	J:247954
	abnormal olfactory sensory neuron morphology	J:247954
	abnormal olfactory sensory neuron physiology	J:247954
	normal behavior/neurological phenotype	J:247954
	decreased olfactory sensory neuron number	J:247954
	decreased survivor rate	J:247954
	impaired olfaction	J:247954
	increased neuron apoptosis	J:247954
	postnatal lethality, incomplete penetrance	J:247954
	small olfactory bulb	J:247954
Ric8b^{tm1b(EUCOMM)Hmgu}/Ric8b⁺ C57BL/6N-Ric8b^{tm1b(EUCOMM)Hmgu}/Cnrm	corneal opacity	J:211773
	increased basophil cell number	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
Ric8b^{tm1b(EUCOMM)Hmgu}/Ric8b^{tm1b(EUCOMM)Hmgu} C57BL/6N-Ric8b^{tm1b(EUCOMM)Hmgu}/Cnrm	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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