Pdzd8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdzd8
PDZ domain containing 8
MGI:2677270

30 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdzd8^{tm1b(EUCOMM)Wtsi}/Pdzd8⁺ C57BL/6N-Pdzd8^{tm1b(EUCOMM)Wtsi}/Wtsi	increased blood urea nitrogen level	J:211773
	increased large unstained cell number	J:211773
	increased mean platelet volume	J:211773
Pdzd8^{tm1b(EUCOMM)Wtsi}/Pdzd8^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pdzd8^{tm1b(EUCOMM)Wtsi}	abnormal globus pallidus morphology	J:317428
	abnormal long-term spatial reference memory	J:317428
	abnormal retrosplenial region morphology	J:317428
	decreased anxiety-related response	J:317428
	decreased body length	J:317428
	decreased body weight	J:317428
	decreased brain size	J:317428
	decreased corpus callosum size	J:317428
	decreased paired-pulse facilitation	J:317428
	decreased superior colliculus size	J:317428
	enlarged cerebellum	J:317428
	enlarged hippocampus	J:317428
	enlarged olfactory bulb	J:317428
	increased vertical stereotypic behavior	J:317428
	postnatal growth retardation	J:317428
	preweaning lethality, incomplete penetrance	J:317428
	reduced long-term potentiation	J:317428
	small thalamus	J:317428
Pdzd8^{tm1b(EUCOMM)Wtsi}/Pdzd8^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pdzd8^{tm1b(EUCOMM)Wtsi}/Wtsi	abnormal vibrissa morphology	J:211773
	hyperactivity	J:211773
	increased circulating amylase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating phosphate level	J:211773
	increased circulating triglyceride level	J:211773
	increased lean body mass	J:211773
	increased red blood cell distribution width	J:211773
	short tibia	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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