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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Crb3
crumbs family member 3
MGI:2670904
26 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Crb3tm1.1Bmar/Crb3tm1.1Bmar
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6
preweaning lethality, complete penetrance J:206750
Crb3tm1.1Lprs/Crb3tm1.1Lprs
B6(SJL)-Crb3tm1.1Lprs
no abnormal phenotype detected J:228786
Crb3tm1.2Bmar/Crb3tm1.2Bmar
B6.129(Cg)-Crb3tm1.2Bmar
abnormal club cell morphology J:206750
abnormal intestine morphology J:206750
abnormal lung morphology J:206750
abnormal proximal convoluted tubule brush border morphology J:206750
abnormal pulmonary alveolus morphology J:206750
abnormal pulmonary alveolus wall morphology J:206750
abnormal respiratory motile cilium morphology J:206750
abnormal small intestinal microvillus morphology J:206750
abnormal small intestinal villus morphology J:206750
decreased small intestinal microvillus size J:206750
dilated renal tubule J:206750
fused small intestinal villi J:206750
kidney cyst J:206750
neonatal lethality, complete penetrance J:206750
respiratory distress J:206750
Crb3tm1.2Lprs/Crb3tm1.2Lprs
B6(Cg)-Crb3tm1.2Lprs
abnormal kidney epithelium morphology J:228786
abnormal lung epithelium morphology J:228786
abnormal respiratory conducting tube morphology J:228786
abnormal small intestinal villus morphology J:228786
cyanosis J:228786
fused small intestinal villi J:228786
impaired mucociliary clearance J:228786
perinatal lethality, complete penetrance J:228786
polycystic kidney J:228786
renal interstitial fibrosis J:228786
respiratory distress J:228786
small kidney J:228786

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory