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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Npas4
neuronal PAS domain protein 4
MGI:2664186
14 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Npas4tm1Meg/Npas4tm1Meg
involves: C57BL/6
hyperactivity J:143367
increased anxiety-related response J:143367
normal nervous system phenotype J:143367
premature death J:143367
seizures J:143367
Npas4tm1Ooe/Npas4+
involves: 129/Sv * C57BL/6
premature death J:145569
Npas4tm1Ooe/Npas4tm1Ooe
involves: 129/Sv * C57BL/6
abnormal behavior J:145569
abnormal neuron morphology J:145569
gliosis J:145569
increased sensitivity to xenobiotic induced morbidity/mortality J:145569
increased susceptibility to neuronal excitotoxicity J:145569
myoclonus J:145569
neuron degeneration J:145569
premature death J:145569
Npas4tm2Meg/Npas4tm2Meg
Not Specified
abnormal inhibitory postsynaptic currents J:143367
abnormal miniature excitatory postsynaptic currents J:143367

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory