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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pla2g3
phospholipase A2, group III
MGI:2444945
27 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pla2g3tm1Murm/Pla2g3+
involves: 129S/SvEv * C57BL/6J
decreased fertilization frequency J:161462
decreased litter size J:161462
decreased sperm progressive motility J:161462
embryonic lethality before implantation, complete penetrance J:161462
reduced activated sperm motility J:161462
reduced male fertility J:161462
Pla2g3tm1Murm/Pla2g3tm1Murm
involves: 129S/SvEv * C57BL/6
abnormal body temperature J:197334
abnormal mast cell differentiation J:197334
abnormal mast cell morphology J:197334
decreased mast cell degranulation J:197334
decreased susceptibility to type I hypersensitivity reaction J:197334
ear inflammation J:197334
edema J:197334
Pla2g3tm1Murm/Pla2g3tm1Murm
involves: 129S/SvEv * C57BL/6J
abnormal acrosome morphology J:161462
abnormal caput epididymis morphology J:161462
abnormal fertilization J:161462
abnormal male germ cell morphology J:161462
abnormal male reproductive system physiology J:161462
abnormal phospholipid level J:161462
abnormal preimplantation embryo development J:161462
abnormal sperm axoneme morphology J:161462
abnormal sperm physiology J:161462
coiled sperm flagellum J:161462
decreased fertilization frequency J:161462
decreased litter size J:161462
decreased sperm progressive motility J:161462
embryonic lethality before implantation, complete penetrance J:161462
globozoospermia J:161462
impaired fertilization J:161462
kinked sperm flagellum J:161462
multiflagellated sperm J:161462
reduced activated sperm motility J:161462
reduced male fertility J:161462

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory