Mdga2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
MGI:2444706

27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mdga2^{Tg(Prnp-PFN1*G118V)838Kiaei}/Mdga2⁺ involves: C57BL/6N	abnormal action potential	J:241428
	abnormal ankle joint morphology	J:241428
	abnormal gait	J:241428
	abnormal motor capabilities/coordination/movement	J:241428
	abnormal motor neuron dendrite morphology	J:241428
	abnormal neuromuscular synapse morphology	J:241428
	abnormal sciatic nerve morphology	J:241428
	abnormal spinal cord morphology	J:241428
	abnormal spinal cord ventral horn morphology	J:241428
	abnormal ventral spinal root morphology	J:241428
	abnormal Wallerian degeneration	J:241428
	astrocytosis	J:241428
	axon degeneration	J:241428
	decreased locomotor activity	J:241428
	hindlimb paralysis	J:241428
	impaired coordination	J:241428
	kyphosis	J:241428
	limb grasping	J:241428
	microgliosis	J:241428
	motor neuron degeneration	J:241428
	premature death	J:241428
	progressive muscle weakness	J:241428
	short stride length	J:241428
	skeletal muscle atrophy	J:241428
	spasticity	J:241428
	tremors	J:241428
	weight loss	J:241428

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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