Sh3rf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sh3rf2
SH3 domain containing ring finger 2
MGI:2444628

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sh3rf2^tm1Zhxu/Sh3rf2⁺ C57BL/6-Sh3rf2^tm1Zhxu	abnormal afterhyperpolarization	J:270945
	abnormal miniature excitatory postsynaptic currents	J:270945
	abnormal nervous system electrophysiology	J:270945
	abnormal nest building behavior	J:270945
	abnormal response to social novelty	J:270945
	abnormal social investigation	J:270945
	decreased vocalization	J:270945
	hyperactivity	J:270945
	increased stereotypic behavior	J:270945
	increased vertical activity	J:270945
	postnatal growth retardation	J:270945
	postnatal lethality, incomplete penetrance	J:270945
	seizures	J:270945
Sh3rf2^tm1Zhxu/Sh3rf2⁺ Tg(Thy1-EGFP)MJrs/0 involves: C57BL/6 * C57BL/6J * CBA	abnormal dendritic spine morphology	J:270945
	abnormal hippocampal pyramidal neuron dendrite morphology	J:270945
	abnormal hippocampus morphology	J:270945
	increased dendritic spine density	J:270945
Sh3rf2^tm1Zhxu/Sh3rf2^tm1Zhxu C57BL/6-Sh3rf2^tm1Zhxu	postnatal growth retardation	J:270945
	postnatal lethality, incomplete penetrance	J:270945
	prenatal lethality, incomplete penetrance	J:270945

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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