Fitm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fitm2
fat storage-inducing transmembrane protein 2
MGI:2444508

30 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fitm2^{tm1.1(KOMP)Vlcg}/Fitm2⁺ C57BL/6N-Fitm2^{tm1.1(KOMP)Vlcg}/J	abnormal lens morphology	J:211773
	decreased prepulse inhibition	J:211773
Fitm2^{tm1.1(KOMP)Vlcg}/Fitm2^{tm1.1(KOMP)Vlcg} C57BL/6N-Fitm2^{tm1.1(KOMP)Vlcg}/J	abnormal pericardium morphology	J:211773
	embryonic growth retardation	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Fitm2^tm1.1Dls/Fitm2^tm1.1Dls Tg(Fabp4-cre)1Rev/? involves: 129S6/SvEvTac * C57BL/6J	abnormal brown fat cell morphology	J:212437
	abnormal fatty acids level	J:212437
	abnormal glucose homeostasis	J:212437
	abnormal white adipose tissue morphology	J:212437
	abnormal white adipose tissue physiology	J:212437
	abnormal white fat cell morphology	J:212437
	normal behavior/neurological phenotype	J:212437
	decreased brown fat lipid droplet number	J:212437
	normal growth/size/body region phenotype	J:212437
	normal homeostasis/metabolism phenotype	J:212437
	increased body weight	J:212437
	increased brown fat cell lipid droplet size	J:212437
	increased circulating insulin level	J:212437
	increased circulating tumor necrosis factor level	J:212437
	increased liver weight	J:212437
	insulin resistance	J:212437
	pale liver	J:212437
Fitm2^tm1Nani/Fitm2⁺ Not Specified	normal cardiovascular system phenotype	J:303195
	decreased heart left ventricle size	J:303195
	decreased heart right ventricle weight	J:303195
	decreased susceptibility to induced morbidity/mortality	J:303195
	normal growth/size/body region phenotype	J:303195
	normal mortality/aging	J:303195
	normal respiratory system phenotype	J:303195
Fitm2^tm1Nani/Fitm2^tm1Nani Not Specified	embryonic lethality during organogenesis, complete penetrance	J:303195

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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