Fgd5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fgd5
FYVE, RhoGEF and PH domain containing 5
MGI:2443369

29 phenotypes from 4 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fgd5^em1(IMPC)Mbp/Fgd5⁺ C57BL/6NCrl-Fgd5^em1(IMPC)Mbp/MbpMmucd	abnormal behavior	J:211773
	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal neural tube morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	abnormal retina blood vessel morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased anxiety-related response	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating glucose level	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	decreased thigmotaxis	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
	enlarged spleen	J:211773
	increased heart weight	J:211773
	increased red blood cell distribution width	J:211773
	persistence of hyaloid vascular system	J:211773
	small liver	J:211773
	small testis	J:211773
Fgd5^em1(IMPC)Mbp/Fgd5^em1(IMPC)Mbp C57BL/6NCrl-Fgd5^em1(IMPC)Mbp/MbpMmucd	abnormal neural tube morphology	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Fgd5^tm1Djr/Fgd5^tm1Djr involves: C57BL/6NTac	embryonic lethality during organogenesis, complete penetrance	J:214520
Fgd5^tm2Djr/Fgd5^tm2Djr involves: C57BL/6NTac	embryonic lethality during organogenesis, complete penetrance	J:214520
Fgd5^{tm3(cre/ERT2)Djr}/Fgd5^{tm3(cre/ERT2)Djr} involves: C57BL/6NTac	embryonic lethality during organogenesis, complete penetrance	J:214520

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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