Cpeb3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cpeb3
cytoplasmic polyadenylation element binding protein 3
MGI:2443075

32 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cpeb3^em1Gaoxu/Cpeb3^em1Gaoxu C57BL/6J-Cpeb3^em1Gaoxu	decreased circulating estradiol level	J:323073
	decreased corpora lutea number	J:323073
	decreased granulosa cell proliferation	J:323073
	decreased litter size	J:323073
	decreased ovary weight	J:323073
	decreased primary ovarian follicle number	J:323073
	decreased primordial ovarian follicle number	J:323073
	decreased secondary ovarian follicle number	J:323073
	decreased superovulation rate	J:323073
	decreased tertiary ovarian follicle number	J:323073
	impaired ovarian folliculogenesis	J:323073
	increased atretic ovarian follicle number	J:323073
	increased circulating follicle stimulating hormone level	J:323073
	increased granulosa cell apoptosis	J:323073
	oocyte degeneration	J:323073
	ovary atrophy	J:323073
	premature ovarian failure	J:323073
	reduced female fertility	J:323073
	small ovary	J:323073
Cpeb3^tm1.2Yshu/Cpeb3^tm1.2Yshu involves: 129S4/SvJae * C57BL/6	abnormal calcium ion homeostasis	J:202741
	abnormal dendritic spine morphology	J:202741
	abnormal hippocampus pyramidal cell morphology	J:202741
	abnormal long-term depression	J:202741
	abnormal neuron physiology	J:202741
	abnormal spatial reference memory	J:202741
	normal behavior/neurological phenotype	J:202741
	decreased locomotor activity	J:202741
	enhanced contextual conditioning behavior	J:202741
	normal growth/size/body region phenotype	J:202741
	increased anxiety-related response	J:202741
	normal nervous system phenotype	J:202741
	reduced female fertility	J:202741
	normal vision/eye phenotype	J:202741

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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