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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Paxx
non-homologous end joining factor
MGI:2442831
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atmtm1Awb/Atmtm1Awb
Paxxem1Spj/Paxxem1Spj
involves: A/J * C57BL/6NTac 		abnormal class switch recombination J:236776
decreased B cell number J:236776
decreased splenocyte number J:236776
decreased T cell number J:236776
normal mortality/aging J:236776
Paxxem1Spj/Paxxem1Spj
Lig4tm1Fwa/Lig4tm1Fwa
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac 		prenatal lethality, complete penetrance J:236776
Paxxem1Spj/Paxxem1Spj
Nhej1tm1Fwa/Nhej1tm1Fwa
involves: 129S6/SvEvTac * C57BL/6NTac 		abnormal thymus involution J:236776
absent lymphocyte J:236776
athymia J:236776
chromosomal instability J:236776
decreased birth body size J:236776
decreased body size J:236776
decreased body weight J:236776
decreased embryo size J:236776
decreased fetal size J:236776
decreased fetal weight J:236776
decreased spleen weight J:236776
decreased splenocyte number J:236776
increased neural tube apoptosis J:236776
lethality throughout fetal growth and development, incomplete penetrance J:236776
postnatal lethality, incomplete penetrance J:236776
small spleen J:236776
Paxxem1Spj/Paxxem1Spj
Xrcc5tm1Nus/Xrcc5tm1Nus
involves: C57BL/6 * C57BL/6NTac 		postnatal lethality, incomplete penetrance J:236776
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory