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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tigar
Trp53 induced glycolysis regulatory phosphatase
MGI:2442752
8 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
TigarGt(EUCE0047g05)Hmgu/TigarGt(EUCE0047g05)Hmgu
involves: 129P2/OlaHsd
abnormal small intestinal crypt cell physiology J:198650
abnormal small intestinal crypt cell proliferation J:198650
increased cellular sensitivity to alkylating agents J:198650
increased cellular sensitivity to gamma-irradiation J:198650
increased sensitivity to xenobiotic induced morbidity/mortality J:198650
increased small intestinal crypt cell apoptosis J:198650
increased susceptibility to induced colitis J:198650
oxidative stress J:198650
Tigartm1.1Khv/Tigartm1.1Khv
Tg(CMV-cre)1Cgn/0
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL
increased susceptibility to induced colitis J:198650

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory